Crème PIGM 400 reduces dark spots and evens skin tone within 4–8 weeks of consistent use. Powered by plum extract, soy isoflavones, and anti-pigment peptides, it brightens without irritation.
It definitely stands out for its subtle but powerful results. At KarinaNYC, we’ve seen it transform clients’ skin when used correctly. In this guide, we’ll share real results, how to use it, and whether it’s right for you.
Keep reading to uncover what others don’t tell you.
Inside Crème Pigm 400: What Makes It A Pigment Game-Changer
Crème PIGM 400 isn’t just a “moisturizer.” It’s a strategic, multi-layered pigment correction treatment disguised as a cream.
It targets pigmentation at three critical stages, it:
slows melanin production
blocks its transfer to skin cells
neutralizes oxidation that makes dark spots stick around longer
It’s packed with serious actives like plum pulp extract, chestnut seed, and wasabi ferment (yes, wasabi!). But don’t worry, it’s fragrance-free and surprisingly gentle.
In clinical tests, PIGM 400 showed a 9% reduction in pigmentation over 56 days. When it’s layered right, especially over the correct P50 and paired with sunscreen, the transformation is visible and lasting.
This cream doesn’t just fade pigment. It protects your results, too.
How It Compares To Other BR Moisturizers
Now, I love my BR creams. I’ve got them all on my shelf, and they each have their moment.
But if you’re dealing with stubborn pigmentation, sun damage, acne marks, dull patches, Crème PIGM 400 is the one you reach for.
Crème Grand Millésime is your classic antioxidant hero, fantastic for skin that needs a refresh.
Crème Splendide is all about lifting and firmness, especially if you’re feeling a little gravity.
Crème Dermopurifiante is perfect for breakout-prone or inflamed skin, it purifies, soothes, and restores balance.
Crème aux Acides de Fruits gives you glow with a light exfoliating touch. Beautiful before events.
Crème Elastine is a must if you’re starting to see fine lines or loss of elasticity, it smooths and softens beautifully.
Crème Iso-Placenta is a post-acne essential, restorative, healing, and perfect for compromised or recovering skin.
But none of them touch pigment the way PIGM 400 does. This cream is made for people who are serious about tackling dark spots without bleach or harsh acids.
If you want something that brightens, protects, and evolves with your skin, this is your go-to. Particularly if your skin is beginning to show signs of sun exposure from the past.
Who Should Use Crème PIGM 400?
Crème PIGM 400 is a product that actually considers how real skin behaves, not how it looks in perfect lighting. It works beautifully across all skin types, but it shines, literally and figuratively, on clients dealing with:
Sun-induced hyperpigmentation from years at the beach, ski trips, or just daily city exposure
Post-acne marks that linger long after the breakout is gone
Uneven tone and dullness that no amount of highlighter can fix
What It Won’t Do
If you’re dealing with deep, hormonal melasma, especially from birth control or pregnancy, Crème PIGM 400 alone won’t be enough.
It can soften the edges, yes. But melasma is stubborn. You’ll need a more strategic mix, which we tailor for every client at KarinaNYC.
Also, if your skin leans very dry, don’t expect this to be your only moisturizer.
It’s lightweight and hydrating for most, but dry skin types will want to layer it over something richer, or mix in a drop of something nourishing like Creme VG Derm or even Creme Grand Millésime.
Does This Work On Darker Skin Tones Or Hormonal Pigmentation?
Yes, this cream delivers strong results on medium to deeper skin tones, without dulling or ashy residue. It supports melanin-rich skin while softening visible pigment.
The formulation respects melanin while gently breaking down the uneven buildup.
For hormonal pigmentation, like melasma, you’ll need extra support, think targeted serums and serious SPF. But as part of a full protocol? It’s a powerhouse.
Crème PIGM 400 Before and After: What to Expect
If you’re anything like our clients at KarinaNYC, you want to know exactly what to expect. How soon will you see change? What’s normal? What’s not?
Week 1–2: Subtle Glow, Smoother Texture
The first thing most people notice? Radiance. Not a blinding, fake glow, just a quiet, healthy brightness. Your skin might feel smoother, look more hydrated, and even reflect light differently.
It’s subtle, but if you take a photo in daylight (and please do, same lighting each time!), you’ll see it.
Week 3–4: Fading Of New Dark Spots, Increased Brightness
Pigmentation that’s fresh, like post-acne marks or recent sun spots, starts to fade. That dull, tired tone lifts.
It’s not just the cream fading pigment, it’s also protecting your skin from further darkening, which makes all the difference. You’ll likely feel more confident without makeup around this point.
Week 5–8: Clearer Tone, Less Dullness, Softened Pigmentation Edges
This is where the “after” photos get exciting. The texture improves and the blotchiness fades.
Pigmentation starts to blend into the surrounding skin rather than standing out. You might even get compliments from people who don’t know you’ve changed a thing.
Week 8+: Full Brightening Potential
At this point, the skin has completed a full turnover cycle. If you’ve been consistent with your application, sunscreen, and exfoliation (hello, Lotion P50), you’ll see your clearest tone yet.
I always say the eight-week mark is where the cream reveals its real personality. And if you’ve paired it with the full PIGM system or in-clinic support? Even better.
How To Use Crème PIGM 400 For Maximum Results
This is where I see most people get tripped up, not because the product doesn’t work, but because they’re not using it right. And with something this effective, application matters.
Here’s how I teach my clients at KarinaNYC:
Use it morning and night on clean skin. After you’ve applied Lotion P50 (I’ll get to that), and your serums, press a pea-sized amount into your face. I personally like to warm it in my fingers first, it melts beautifully.
Massage, don’t pat. The actives in Crème PIGM 400 respond better to movement. A light massage helps it penetrate and increases circulation, which supports pigment dispersion.
Follow with SPF every single morning. This cream is non-photosensitizing, but if you skip sunscreen, you're just inviting new spots to take over the space the old ones left behind.
Does It Require Other BR Products?
No. Crème PIGM 400 works as a standalone, but results are amplified when it’s part of a strategic routine. That’s why my team and I customize every Biologique Recherche plan we offer.
When you combine this cream with the right exfoliant, serum, and SPF, your pigment doesn’t stand a chance.
Let me share three of my go-to pairings from the Biologique line. These aren’t part of the “PIGM” family, but they’re total power partners:
Lotion P50 (Original Or PIGM)
Think of this as your primer. It gently exfoliates, balances pH, and clears the way for Crème PIGM to penetrate deeper and work smarter.
Masque Vivant
This is our go-to for congestion, dullness, and tired skin. It detoxifies deeply while refining pores and brightening the overall tone. I call it the “reset button” before any brightening protocol.
Serum Oligo-Protéines Marines
This one’s for tired, dull skin that needs a reset. It supports pigment control and gives your skin that energized, well-rested glow.
Worried It Won’t Work? Let’s Break It Down
We hear it all the time, “What if I spend all this money and it doesn’t work?” You’re not alone. Investing in your skin is personal, and it should come with clarity.
Let’s walk through the usual concerns we hear from clients and what you can actually expect from Crème PIGM 400.
Will The Pigmentation Come Back If I Stop Using It?
Only if you stop protecting your skin. Crème PIGM 400 does the heavy lifting, but SPF is your insurance policy.
If you’re consistent with sunscreen and keep up your maintenance routine, your results will hold.
What If I Don’t See Results In 30 Days?
This is where so many give up too early. You’re building momentum in those first weeks, hydrating, supporting turnover, suppressing new pigment. Stay the course.
If you’re not sure it’s working, that’s when you need a pro’s eye. We’re here for that.
Can I Use This With Tret Or Vitamin C?
Yes, but gently. If you're using tretinoin or high-strength vitamin C, I recommend staggering use (alternate nights) or buffering with a hydrating serum before applying PIGM 400.
Your skin will tell you what it can handle. Don’t force it. It’s better to be consistent than aggressive.
What If My Pigmentation Looks Darker At First?
If your pigmentation looks worse before it gets better, don’t panic. It’s not a reaction. It’s part of the process.
What’s happening is cell turnover is lifting pigment to the surface before it sheds. It can appear darker for a few days or even a week, especially if you’re exfoliating regularly with P50.
That’s your cue to stay the course, not quit early.
How We Get You Clearer Skin, Faster
If you’ve tried high-end brightening creams with no payoff, Crème PIGM 400 might be the first one that delivers.
This cream is powerful, yes, but it’s not magic on its own. It only works beautifully when your routine is tailored to your skin’s real story.
That’s where we come in.
At KarinaNYC, we don’t just sell skincare. We guide you through it. We test every product ourselves (my bathroom cabinet is proof!) and we’ve seen firsthand what works, and what just wastes time and money.
For those who are serious about fading pigmentation and investing in skin that actually glows, we offer more than product, we offer transformation.
Here’s how KarinaNYC makes the difference:
🌿 One-on-One Skincare Consultations - You don’t have to guess. We take a close look at your skin, your history, your triggers. Whether it’s sun, acne, or hormones, we find out what’s behind the pigmentation and build a custom plan around it.
🧴 Authenticated Product Selection - When you buy from us, you know it’s the real deal, properly stored, never heat-shocked or resold. It makes all the difference. We’ve seen too many people buy from marketplaces and wonder why their product feels “off.” It’s not worth the risk.
🧖♀️ In-Clinic Treatments for Faster Results
Sometimes, skin needs a push. Our Biologique facials layer Crème PIGM 400 with lifting massage, LED therapy, and oxygenation to supercharge your results. Think of it as your shortcut to clear, radiant skin.
Your skin tells a story, and when it’s been through sun, stress, or scars, it deserves more than a product. It deserves a strategy. That’s what KarinaNYC does.
And if your story is about finally feeling confident without makeup again, we’d love to help you write that next chapter.
