Apply 1mL of Serum Elastine to clean skin after Lotion P50, morning and/or night, using upward strokes. Ideal for expression lines and loss of firmness, it layers well under moisturizers.
Best results come with consistent use and proper pairing in your routine.
Whether you're noticing fine lines or feeling a lack of bounce, this guide explains exactly how to use it for maximum results.
Ready to elevate your routine? Let’s dive in.
Serums 101: What They Do and Why Your Skin Craves Them
Serums the workhorses of your routine, the formulas that go deeper, act faster, and actually change your skin.
Unlike your cleanser or moisturizer, a serum isn’t just about surface hydration or comfort. It’s pure active ingredients in a lightweight format, designed to target real concerns: wrinkles that don’t bounce back, crepey texture around the eyes, skin that’s lost its “snap.” When someone comes to me wondering why their skincare isn’t working, the answer is almost always: they’re missing the right serum, or using it wrong.
Serum Elastine: The Secret to Skin That Snaps Back
Out of all the Biologique Recherche serums I’ve used (and trust me, I’ve used all of them), Serum Elastine is the one I reach for when skin starts showing early signs of slackening.
Think smile lines that linger a bit longer, forehead creases that don’t smooth out like they used to, or that dull, deflated look after travel or stress.
What makes this serum different is the science behind it.
Elastine uses a unique hexapeptide, what I call the “spring segment” of your skin. This little peptide mimics the core of your natural elastin fibers, signaling your fibroblasts (the cells that build your skin’s scaffolding) to tighten things back up.
It’s not just softening wrinkles, it’s rebuilding bounce.
Best for: Subtle fine lines, dehydration creases, early aging, especially around the eyes, lips, and neck.
Skin types: Every single one. If your skin feels tired, stretched, or just less firm than it used to be, this will support you.
Why it stands out: Most serums in the BR line are issue-specific, pigmentation, redness, hydration. Elastine works underneath all of that. It’s structural. Preventative and corrective. A true essential in any anti-aging routine.
If you’ve ever looked in the mirror and pulled your skin back just to see what it could look like, Serum Elastine is your next step. And yes, I keep it stocked in my personal cabinet at all times.
How to Use Serum Elastine (The Right Way)
It’s not just what you use, it’s how you use it. Technique matters, especially with a serum this powerful. Here’s the quick 4-step method I teach all my clients:
1. Warm It Up
Drop it into your palms (not fingertips), press hands together to activate.
2. Press, Don’t Rub
Gently press into skin with palms, no tugging, no dragging.
3. Lift & Glide
Use upward strokes from the center of the face outwards and up the neck.
4. Tap the Eyes
With your ring finger, tap around the orbital bone, never too close to the lash line.
✨ Pro Tip: Want more lift? Use a clean jade roller or gua sha after.
How to Build a Routine Around Serum Elastine
1. Cleanse Gently, But Thoroughly
Start fresh. I always recommend Lait Dermo-S: it’s gentle, calming, and ideal for sensitive or stressed skin.
It removes impurities without stripping and leaves the skin feeling soft, balanced, and perfectly prepped. No foam, no tight feeling.
2. Tone with Lotion P50
This is your primer. Whether you use P50W (for sensitive skin) or PIGM 400 (for pigment issues), apply it with a cotton pad, press in, and wait 60–90 seconds.
This step balances your skin’s pH and exfoliates just enough to let your serums penetrate deeper.
3. Apply Serum Elastine
Now comes the hero. Depending on where you're applying:
Just the eyes? Use 2–3 drops and gently tap around the orbital bone.
Face and eyes? 6–8 drops.
Face, eyes, and neck? You’ll want 8–10 drops.
4. Follow with Secondary Serums (Optional)
This depends on your needs. Many of my clients layer Serum A-Glyca to prevent glycation, or Serum Placenta for healing. We customize this at KarinaNYC based on skin tension zones and your age.
5. Lock It In
Use a finishing cream like Crème Splendide (firming and rich). You want to seal in all that goodness without blocking absorption.
6. Day or Night Finishing Touch
In the AM, never skip SPF, the sun will undo all your hard work. For evenings or events, I’ll often recommend Masque Biomagic as a finishing layer for taut, radiant skin.
How Often Should You Use Serum Elastine?
Here’s what we advise based on where you’re at:
Preventative care (30s): Start with 3x per week at night. Think of this as training your skin’s elasticity over time.
Visible aging signs: Daily use, morning or night, keeps skin bouncy and lines softened.
Post-procedure or skin under stress: Twice a day. This serum is fantastic post-peel or post-laser to calm, firm, and protect.
Yes, You Can Ask That! Here’s What You Need to Know
Can I Mix It With My Moisturizer?
You can, but I don’t recommend it. Let the serum absorb first on bare skin so it can do its job, then moisturize after.
Should I Wait Between P50 And Elastine?
Yes, wait at least a minute. Let the P50 settle. Your skin needs to be balanced, not damp with exfoliant.
Is It Safe Near The Eyes?
Yes, but don’t get it in your eyes. I tap gently with my ring finger around the orbital bone. It’s incredible for crows’ feet and under-eye creases.
One of the usual mistakes I see? People slather on too much, too fast.
With Elastine, less is more. Think precision, not volume. And if you’re unsure, we can always customize your protocol, because when it’s used right, this serum changes skin.
These Are What Makes Serum Elastine A Game-Changer
When clients ask me what makes Serum Elastine worth it, I tell them this: it shows up in the mirror.
This isn’t one of those serums you hope is working. If used correctly, it gives visible results, and fast. Here’s what you can expect:
Fewer fine lines and less “crease memory.” It softens the expression wrinkles we all collect, those forehead lines, the laugh lines, the subtle ones around the lips that suddenly deepen in your 40s.
Elasticity like you remember. Your skin’s “snap-back” improves because Elastine reactivates the building blocks responsible for firmness.
A stronger foundation. It doesn’t just plump, it strengthens the skin matrix. Think of it as upgrading your skin’s scaffolding from wood to steel.
Perfect for layering. It absorbs quickly, leaves zero residue, and doesn’t pill under makeup or moisturizers.
Tech-neck relief. One of my favorite off-label uses? Apply it to horizontal neck lines from phones and laptops. It relaxes micro-tensions that create those stubborn creases.
⏳ Most of my clients start noticing changes in 10 to 14 days, especially if they’re consistent and following the layering protocol we build for them.
What Not to Use with Serum Elastine
If you’re investing in a high-performance serum like Elastine, the last thing you want is to sabotage it with the wrong product cocktail.
Oil-based products first? Big no. Oils form a barrier that blocks absorption. If you love facial oils, apply them last, not before or immediately after Elastine.
Skip the strong retinols or exfoliants on the same night. You’ll overwhelm the skin barrier. This serum is potent on its own, pair it smartly.
Heavy occlusives before it? Wasteful. Rich creams like balms or petrolatum-based moisturizers block penetration. Always use Elastine first, right after P50, and let it breathe into the skin.
This serum plays well with others, but only if you let it lead. Use it first. Layer it right. Trust the process. I’ve seen it work on thousands of faces, and mine is still proof.
Stop Guessing, This Is How You Get Results
I can’t tell you how often someone comes in saying, “This serum didn’t work for me,” and I find out they were layering it over an oil or using way too much.
Serum Elastine is not a moisturizer, it’s a precision treatment. And like any precision tool, it needs to be used with intention.
If you’re not seeing results, it’s likely one of three things:
You’re using too much or too little (1ml or 6–8 drops is your sweet spot).
You’re applying it at the wrong time in your routine, always after P50, always before moisturizer.
You’re pairing it with products that block or deactivate it (like oils or heavy occlusives too early).
That’s why we don’t just sell skincare at KarinaNYC, we guide you through it. Because when you use it right? Your skin will prove it to you.
🚀 Ready to Upgrade Your Routine?
If you’re someone who’s:
Serious about aging beautifully
Done wasting money on routines that almost work
Ready to stop second-guessing your skincare choices
…then this is your moment. At KarinaNYC, we don’t sell trends, we build skin confidence.
Here’s how I can help you today:
🧪 Virtual Skin Consultation – Let’s take the guesswork out. I’ll match you with exactly what your skin needs, and what to skip.
💎 Authentic BR Products, Shipped Fresh – No expired, heat-damaged serums. Only verified products, stored properly and priced right.
✨ Personalized Layering Protocols – We build your routine like a facial: by skin zone, age, and your skin’s tension points.
Shop smarter. Age gracefully. And never wonder if you're doing it wrong again.
Because when your skincare works, you feel it every time you look in the mirror.