Apply a pea-sized amount of Crème PIGM 400 to clean skin after Lotion P50 and serums, morning and night. Massage gently into face, neck, or spots.
This brightening cream targets hyperpigmentation, but only when used correctly.
At KarinaNYC, we help clients layer it with purpose, not guesswork. Whether you're battling sun damage or dullness, knowing this cream's true power, and how to unlock it, is the key.
Let’s walk you through the how, when, and why to make every drop count.
The Smart Way To Fade Pigmentation: Meet Crème PIGM 400
Crème PIGM 400 from Biologique Recherche is not just another brightening moisturizer. It’s a precision tool.
Designed to target pigmentation at every stage, from how melanin forms to how it shows up on your skin, it works to both fade existing spots and stop new ones from surfacing.
This is my go-to for anyone dealing with:
Sun-damaged skin (those stubborn post-vacation patches)
Post-acne marks that just won’t fade
Hormonal pigmentation and melasma
That overall “dull and uneven” tone that makes skin look tired
Crème PIGM 400 is especially effective for normal, oily, and combination skin, but with the right layering, it works beautifully on dry or lipid-depleted skin too.
That’s where professional guidance matters. At KarinaNYC, we often pair it with Serum PIGM 400 and finishing serum Yall-O2 for brightening.
What sets it apart is how gently it works.
No bleaching, no stripping, and none of the sensitivity you’d expect from typical brighteners or retinols.
With wasabi extract, soy isoflavones, plum pulp, and vitamin E, it restores radiance gradually, and when the glow returns, my clients feel it inside and out.
From Cleanse To Glow: How To Layer Crème PIGM 400 Correctly
Scoop out no more than a pea-sized amount. This isn’t a heavy occlusive cream; it’s active, precise, and designed to absorb quickly when applied the right way.
Apply it to your entire face, neck, and décolleté, or just target specific areas where you see pigmentation, like the upper cheeks, temples, or jawline.
If you're treating melasma or post-acne marks, be intentional: press the cream in gently, then massage it with light upward strokes to encourage circulation and absorption.
Don’t rush this step. Feel the texture and take a breath. This isn’t just about treating spots, it’s about showing up for your skin in a meaningful, consistent way.
For the best absorption, wait 30–60 seconds before applying your next product (like SPF in the morning or a Finishing Serum at night).
Let the cream settle into the skin fully, it’s more effective when it’s not diluted or disturbed.
Bonus Layer: Complexe Royal for Extra Glow
Want to take Crème PIGM 400 to the next level? Add a few drops of Complexe Royal into the cream at night.
This finishing serum, packed with royal jelly and botanicals, boosts radiance and smooths texture, perfect for dull or tired skin.
Blend it in your palm, apply as usual, and wake up to what my clients call the “overnight facial glow.” Simple, luxurious, and totally worth it.
Where Creme PIGM 400 Fits In Your Routine
This is where the magic really happens. Crème PIGM 400 isn't a standalone fix, it’s the power player in a larger strategy. At KarinaNYC, I always teach my clients that this formula only performs at its best when layered thoughtfully.
When the right products support it, that’s when the real transformation begins.
1. Lait Cleanser
Start with Lait EV, Lait SR, or Lait Dermo-S depending on your skin type.
Lait EV is ideal for dry, mature skin, it comforts and nourishes as it cleanses.
Lait SR is perfect for oily or congested skin, it purifies without stripping.
Lait Dermo-S is ultra-gentle, made for reactive or barrier-impaired skin.
Clean skin is non-negotiable, this step preps the canvas.
2. Lotion P50 PIGM 400
Apply P50 PIGM 400 with a cotton pad using the press-and-roll method. This exfoliates gently, balances pH, and preps your skin to actually absorb the brightening actives that follow.
3. Serum PIGM 400
Dispense a few drops of Serum PIGM 400 and press into the face, neck, and décolleté, or just dark-spot areas if you're spot-treating.
This serum targets pigmentation at the source and builds a synergistic base for Crème PIGM 400.
4. Crème PIGM 400
Apply a pea-sized amount and massage into the skin with gentle upward strokes. Focus on areas prone to pigmentation like cheekbones, upper lip, or jawline.
5. Sunscreen (AM)
Always finish with a broad-spectrum SPF 50. Without this layer, you’re leaving the door wide open for pigmentation to return.
Think of SPF as your skin’s security guard.
Frequency by Skin Type
Oily/Normal Skin: Use it morning and evening.
Dry/Lipid-Depleted Skin: Use it once daily, usually at night, and pair with T.E.W.L. for extra comfort.
Reactive/Sensitized Skin: Wait until your barrier is repaired, then start 3x/week and build up gradually.
Fading Spots Takes Time, Here’s What to Expect
Crème PIGM 400 doesn’t just brighten, it re-educates your skin.
But only if you give it the time and consistency it deserves. Here’s the timeline I set with every serious pigmentation client:
Week 2:
You’ll start to notice a healthier, more radiant tone. Your skin will feel more balanced, with a subtle brightness that makes it look “awake,” even without makeup.
Week 4:
Early pigmentation, like light sun damage or dull patches, begins to soften. Texture often improves, and your overall tone looks more even, especially with daily SPF support.
Week 6–8:
Deeper spots (melasma, post-acne marks) start fading. They look less sharp, more diffused. Clients often say they feel confident wearing less concealer, or none at all.
Ongoing:
With proper maintenance, you prevent new pigmentation from forming. That’s the long-term win: skin that stays clear, luminous, and even through every season.
The biggest mistake? Quitting too early.
Hyperpigmentation has a memory. It took years to form, it won’t disappear overnight. But with the right routine, it absolutely will fade.
What Crème PIGM 400 Does For Your Skin (When Used Right)
When people ask me why I trust Crème PIGM 400 so much, I always say, it’s the quiet achiever in the Biologique Recherche line.
It doesn’t scream or sting. It doesn’t promise overnight miracles. What it does? It works, subtly, steadily, beautifully.
Immediate Radiance Boost
Within days, clients tell me their skin looks “more awake.” That’s the brightening complex at work, improving tone without irritation.
Targets Melanin Synthesis and Migration
This isn’t surface-level skincare. PIGM 400 goes deeper, interrupting melanin formation and blocking its transfer to the surface. That’s why it works so well on stubborn pigmentation.
Reduces Post-Summer Sun Damage
Fall is our most popular season for this cream, after months of sun, it helps undo the damage and reset your tone. Think of it as a pigment detox.
Non-Photosensitizing, Safe for All Seasons
Unlike acid-heavy brighteners or retinol, Crème PIGM 400 doesn’t make you sun-sensitive. Use it year-round, as long as SPF is part of your routine.
Pairs Seamlessly With BR’s Clinical-Level Protocols
Whether you’re doing LED, light peels, or using Quintessential Serums, this cream integrates effortlessly. It’s not fussy, it’s functional.
That’s why it’s part of so many custom routines I build at KarinaNYC.
If you’ve tried brightening creams that overpromised and underdelivered, this one is worth your patience.
The more consistently you use it, the more your skin rewrites its story, from tired and blotchy to smooth, luminous, and balanced.
Let’s Clear This Up: Questions I Hear All the Time
You’re not the only one with questions, my clients ask these all the time.
Here’s what you need to know to use Crème PIGM 400 confidently and correctly from day one.
Can I Use It With Vitamin C?
Yes, but be strategic. I usually alternate or apply Vitamin C in the morning and PIGM 400 in the evening unless your skin can handle layering, talk to me or your esthetician first.
Will It Cause Purging?
No. Unlike retinols or exfoliating acids, Crème PIGM 400 doesn’t force your skin to “push things out.” It works calmly and intelligently.
Does It Lighten Freckles?
It doesn’t bleach. It helps fade unwanted pigmentation but leaves your natural tone intact. Think refined, not erased.
What If It Pills Under My Makeup?
Pilling is usually a sign you’re using too much or pairing it with an incompatible serum. Try reducing the amount or switching your layering technique.
Ready for Real Results?
You’ve seen the guides. You’ve heard the stories. But if your dark spots aren’t budging, the issue might not be the product: it’s how you're using it.
Most pigmentation treatments fail not because they’re weak, but because they’re misused.
At KarinaNYC, we don’t guess. We build precision routines that work.
✨Free Personalized Skincare Consult
Get matched with the right support serums and finishers for Crème PIGM 400. We don’t just sell, we solve.
🧴BR Starter Routine Kits
Our curated PIGM sets take out the guesswork. These kits are carefully built to work with your skin’s current state, available exclusively through KarinaNYC.
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Your skin is unique. Your routine should be too. Let’s get it right, together.
